Potassium Azeloyl Diglycinate for Acne - Benefits & Uses

Potassium Azeloyl Diglycinate for Acne - Benefits & Uses

Struggling with acne? Here at DMD Skin Sciences, we're always searching for effective solutions that are gentle enough for everyday use. That's why we're excited about potassium azeloyl diglycinate, or PAD for short. In fact, this was how excited our team was:

 

@dr.mike.d Us when we found out about Potassium Azeloyl Diglycinate. 🤭 Happy Bday @Christian Bables #LearnItOnTiktok #tiktokquiz #fyp #foryou #acnescars #acnescarph #dermph #dermatologist #dermatologistph #dermatologistphilippines #acneexpert #acne #acnecure #azelane #acnetreatmentph acne #acnetreatment #acnetreatmentphilippines #skintok #edutok #tiktoku #tiktokskwela #eduwow #learnontiktok #skincare #hormonalacne #backtotiktokskwela #healthtokph #acnederm #acnederma #acnedermatologist #acnefree #acnejourney #acnebreakouttreatment #acnepimplesremoval #acnescarsremoval #acnedoctor #creatorshortvideo ♬ original sound - renz michael

 

This ingredient is actually derived from azelaic acid, a well-known acne fighter, but PAD is specially formulated to be gentler on your skin while still delivering those same powerful acne-clearing benefits.

Want to learn more about PAD and how it could help clear your skin? Keep reading because we've got all the details coming up!

What is Potassium Azeloyl Diglycinate?

As mentioned above, PAD is a derivative of azelaic acid, but what exactly does that mean? Skincare scientists take azelaic acid and combine it with glycine (a moisture-loving ingredient) and potassium hydroxide to create PAD.  This makes it much easier for skincare brands to work with, since unlike regular azelaic acid, PAD mixes well with water. Plus, thanks to that added glycine, you get the bonus of extra hydration while fighting acne; something regular azelaic acid can't offer!

Benefits of PAD for Skin

PAD's main superstar quality is its acne-fighting power. It helps control oil production and tackles those pesky breakouts by reducing bacteria and unclogging pores, all while being gentle enough for daily use.

But there's more than just fighting acne. Here are other potassium azeloyl diglycinate benefits:

  • Controls Oil Without Drying: If you have oily skin, PAD helps keep that excess shine in check while still maintaining your skin's moisture balance. No more choosing between being oily or dried out!
  • Brightens and Evens Skin Tone: Those dark spots from old breakouts? PAD helps fade them by working on the pigment-producing process in your skin, giving you a more even, glowing complexion over time.
  • Keeps Skin Hydrated: Thanks to its special formulation with glycine, PAD helps moisturize your skin while it works. This means no tight, uncomfortable feeling that you might get with other acne treatments.
  • Improves Overall Skin Texture: With regular use, PAD helps smooth out your skin's texture, making it look and feel softer. It even helps with fine lines.
  • Super Gentle: Unlike some harsh acne treatments that can leave your skin red and angry, PAD is formulated to be super gentle. This makes it ideal for you if you have sensitive skin or if other acne products have been too intense for you.

PAD vs. Azelaic Acid

Now you might be wondering why you should use a derivative of azelaic acid instead of azelaic acid itself. Why consider potassium azeloyl diglycinate vs. azelaic acid? Here are a few reasons: 

  • Gentler Formulation: While both ingredients are effective, PAD is specifically designed to be gentler on the skin. It doesn't have the same stinging effect as azelaic acid, which can be a major plus for those with hypersensitive skin. This makes PAD a top choice for individuals with conditions like rosacea, a common skin condition that often causes redness and visible blood vessels in the face. If you've found azelaic acid a bit too strong for regular use, PAD might be the perfect alternative.
  • Better Absorption: One of PAD's standout features is how easily it's absorbed into the skin. Its water-soluble nature means it can penetrate more easily, delivering those amazing skin benefits right where they're needed. This also makes it lighter and more friendly to acne-prone and oily skin, as it won't sit heavily on the surface or clog pores.
  • Added Hydration Benefits: As mentioned above, thanks to its formulation with glycine, PAD has moisturizing properties. PAD helps maintain your skin's hydration level to help maintain a healthy skin barrier.
  • Similar Effectiveness: You're getting the same core benefits that made azelaic acid famous—acne control, evening skin tone, and improving texture—just in a form that might work better for your skin's needs. 

How to Use PAD

You'll find PAD in various skincare products like serums, creams, and toners. Some are available over the counter, while others might be part of professional skincare lines. But before you dive in, here's what you need to know about using PAD:

Start Slow and Steady

Even though PAD is gentler than many active ingredients, it's always smart to introduce any new skincare product gradually. Start by using it every other day, then increase to daily use as your skin adjusts.

Do a Patch Test

We always recommend doing a patch test before trying any new skincare ingredient. Apply a small amount to your inner arm or behind your ear, and wait 24 to 48 hours to make sure your skin gets along with it. If you're unsure about anything regarding patch testing or the use of PAD, you can always contact us at DMD Skin Sciences—we'll be happy to guide you!

Best Practices for Using PAD

Do the following so you can get the most out of your PAD products:

  • Apply to clean, dry skin so PAD can be properly absorbed without any disruptions.
  • Use in your treatment step (after cleansing but before moisturizing) to maximize its effectiveness.
  • Follow up with a moisturizer to lock in the benefits and keep your skin hydrated. Try our MISSION: SKIN° HydroLock Lite Moisturizing Cream. Its light, fast-absorbing formula helps maintain your skin barrier while keeping your skin smooth and supple.
  • Don't forget your sunscreen during the day. For your face, try FREZYDERM Face Sunscreen SPF50. It's perfect for acne-prone skin with a velvety, matte finish and no white cast. For body protection, we have two great options. MONT DE LUR Moisturizing Body Sunscreen SPF50 PA++++ offers lightweight, highly moisturizing coverage that absorbs quickly without leaving any white cast.  If you prefer an even lighter feel, try the MONT DE LUR Crystal Serum Sunscreen SPF50 PA++++. It provides powerful broad-spectrum protection in a barely-there serum formulation that's perfect for oily, acne-prone, and sensitive skin.

Ready to Try PAD? 

You can find these effective PAD products at DMD Skin Sciences:

  • MISSION: SKIN° SpotLite Acne Spot Concentrate: This targeted 10mL treatment is your go-to for dealing with specific breakout areas. Its unique double-action Acnomelan formula not only treats active acne but also helps fade those stubborn dark spots left behind. The PAD in this formula works to calm inflammation while preventing further pigmentation.
  • ETHERIUS. Azelure PAD Serum: This lightweight 30mL serum is perfect for all-over treatment, helping to prevent breakouts before they start. It regulates oil production, fights bacteria, and soothes the skin - all while feeling non-sticky and comfortable. Plus, it helps address those annoying red acne marks we all want to fade. Its anti-inflammatory property proves helpful in improving skin redness in conditions such as rosacea.

These dermatologist-developed products are formulated to give you the full benefits of PAD in its most effective form. Whether you're dealing with occasional spots or looking for overall skin improvement, we've got you covered!

Side Effects of PAD

Clinical studies have shown that PAD has a favorable safety profile, with research demonstrating minimal adverse reactions in participants. However, as with any skincare ingredient, it's important to understand potential side effects:

  • Skin Irritation: Even though PAD is designed to be gentle, you might experience mild side effects like redness or itching when you first start using it. This typically happens during the initial application phase and when used excessively. Please carefully follow the instructions of use on the skincare’s label.
  • Allergic Reactions: While uncommon, allergic reactions are possible. Watch out for symptoms like rash, swelling, or hives. If you know you're sensitive to azelaic acid or glycine, be sure to do a patch test before using PAD products on your face. You can also keep antihistamines like levocetirizine close by to counteract allergies.
  • Skin Dryness: You might notice some dryness or flaking, particularly if you're using PAD alongside other exfoliating products. This is why following up with a good moisturizer is so important.
  • Product Interactions: Be careful when using PAD with other active ingredients, especially retinoids or strong exfoliants. Using multiple active ingredients together can increase the risk of irritation.

If you experience any of these side effects, especially if they're severe or persistent, stop using the product and consult with a board-certified dermatologist. They can help determine if PAD is right for your skin and suggest the best way to use it.

Conclusion

Potassium azeloyl diglycinate's skin benefits are clear - it effectively fights acne and fades dark spots while being gentler than traditional treatments. It's a smart choice if you've found other acne treatments too harsh or are looking for something that tackles multiple skin concerns at once.

Have other skin concerns? Whether you're dealing with acne, oily skin, large pores, or other skin concerns, DMD Skin Sciences is here to help. Our dermatologist-tested, science-backed solutions and deep understanding of Filipino skin needs have helped countless people achieve clear, strong skin. 

Let us help you find the perfect solutions for your unique concerns. Reach out to us today—we look forward to being part of your journey to healthier, more confident skin!

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